7,8-Dihydroxyflavone 38183 03-8

Product Name: 7,8-Dihydroxyflavone (7,8-DHF)
CAS Number: 38183-03-8
Appearance: Yellow Powder
Purity: 99%

Product Description:

7,8-Dihydroxyflavone (7,8-DHF) is a high-purity compound recognized for its role as a potent and selective TrkB receptor agonist (Kd ≈ 320 nM). The TrkB receptor is a critical mediator of brain-derived neurotrophic factor (BDNF) signaling, which plays a vital role in neuronal development, survival, and synaptic plasticity.

Applications:

• Biological Research: Widely used in neuroscience to study mechanisms related to neuroprotection, synaptic plasticity, and cognitive functions.
• Pharmaceutical Research: Investigated as a potential therapeutic agent for neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease.
• Cancer Studies: Whiteheadoginoside B4, structurally related, is noted for its application in liver cancer research.

Features:

• High Purity: Ensures reliability in research and experimental reproducibility.
• Stable in Solid Form: Ideal for long-term storage under recommended conditions.

Storage Information:

• Conditions: Store under an inert atmosphere at room temperature in a tightly sealed container to protect from moisture.
• Stability: Solid form remains stable for up to 1 year. DMSO or ethanol solutions are stable for up to 1 week when stored at -20°C.